Objectives

• To explore differences in patient’s health preferences by disease area

• To assess preferences from adolescents and compare these to general population preferences for adolescents

• To develop value sets for young populations using the EQ-5D-Y instrument

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Methodology

• This WP will use discrete choice experiments (DCE) to obtain health state preferences from different subpopulations. This includes adult patients, adult general population and adolescent general population.

• Health state preferences for different groups of patients in a sample of 1400 in two countries, 700 each (Germany and Spain), will be investigated using the EQ-5D-5L instrument.

• Using the EQ-5D-Y instrument, child health state preferences in a sample of 4200 respondents from the general population in 3 countries - 1400 respondents (700 adults, 700 adolescents) from each of Slovenia, Germany and Spain, will be investigated.

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Outputs

• Deliverable D5.1: Value sets for the EQ-5D-Y in Germany, Slovenia and Spain and comparison of EQ-5D-Y value sets across countries (Germany, Slovenia and Spain) [PDF]
   

• Deliverable D5.2: Comparison of EQ-5D-5L value sets from different disease areas in 2 countries (Germany and Spain) [PDF]
   

• Work Package Overall Results – Poster [PDF]
   

• Dataset on adolescent preferences toward EQ-5D-Y in Slovenia [PDF]
   

• Dataset on adult preferences toward EQ-5D-Y health states in Slovenia [PDF]
   

• Dataset on preferences of diabetic patients toward EQ-5D5L health states in Germany [PDF]
   

• Dataset on preferences of rheumatic patients toward EQ5D-5L health states in Germany [PDF]
   

• Dataset on preferences of diabetic patients toward EQ-5D5L health states in Spain [PDF]
   

• Dataset on preferences of rheumatic patients toward EQ5D-5L health states in Spain [PDF]
   

• Dataset on adult preferences toward EQ-5D-Y health states in Germany [PDF]
   

• Dataset on adolescent preferences toward EQ-5D-Yin Germany [PDF]
   

• Dataset on adult preferences toward EQ-5D-Y health states in Spain [PDF]
   

• Dataset on adolescent preferences toward EQ-5D-Yin Spain [PDF]

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Publications

• Prevolnik Rupel V, Ogorevc M, IMPACT HTA HRQoL Group. et al (2021). EQ-5D-Y value set for Slovenia. PharmacoEconomics. [https://doi.org/10.1007/s40273-020-00994-4]
   

• Ludwig K, Ramos-Goñi JM, Oppe M, Kreimeier S, Greiner W (2021). To what extent do patient preferences differ from general population preferences? Value in Health.  [https://doi.org/10.1016/j.jval.2021.02.012]
   

• Prevolnik Rupel V, Ramos-Goñi JM, Ogorevc M, Kreimeier S, Ludwig K, Greiner W (2021). Comparison of adult and adolescent preferences toward EQ-5D-Y-3L health states. Value in Health. [www.sciencedirect.com/science/article/pii/S1098301521015266]
   

• Ramos-Goñi JM, Oppe M, Estévez-Carrillo A, Rivero-Arias O, Wolfgang G, Kreimeier S, Ludwig K, Rupel V (2021). Accounting for unobservable preference heterogeneity and evaluating alternative anchoring approaches to estimate country-specific EQ-5D-Y value sets: A case study using Spanish preference data. Value in Health. [https://doi.org/10.1016/j.jval.2021.10.013].
   

• Kreimeier S, Mott D, Ludwig K,  Greiner W (2022). EQ-5D-Y Value Set for Germany. PharmacoEconomics. [https://doi.org/10.1007/s40273-022-01143-9]

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